MetAP-2 inhibitor polymersomes for therapeutic adm

专利名称：MetAP-2 inhibitor polymersomes for

therapeutic administration

发明人：ベニー－ラトサビー オフラ申请号：JP2010515120申请日：20080626公开号：JP20105316A公开日：20100930

专利附图：

摘要：Described herein are MetAP-2 inhibitors and compositions and formulationsthereof, and more particularly compositions and formulations of MetAP-2 inhibitorswherein the MetAP-2 inhibitor is associated with a block copolymer comprising ahydrophilic polymer moiety and a hydrophobic polymer moiety. The present inventionalso relates to compositions and formulations comprising MetAP-2 inhibitors for oraladministration or administration via routes such as topical or ocular administration. The

present invention also provides methods to treat conditions associated with or related tothe over-expression or over-activity of MetAP-2 by administering the compositions andformulations comprising MetAP-2 inhibitors as disclosed herein.

申请人：チルドレンズ メディカル センター コーポレーション

地址：アメリカ合衆国マサチューセッツ州０２１１５，ボストン，シャタック・ストリート ５５

国籍：US

代理人：清水 初志,春名 雅夫,山口 裕孝,刑部 俊,井上 隆一,佐藤 利光,新見 浩一,小林 智彦,渡邉 伸一,大関 雅人,川本 和弥

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