SEPARATION MATRICES FOR PURIFICATION OF BIOLOGICAL

专利名称：SEPARATION MATRICES FOR PURIFICATION

OF BIOLOGICAL PARTICLES

发明人：MALOISEL, Jean-Luc,BUSSON,

Karolina,LACKI, Karol,NOREN,Bjorn,SKOGLAR, Helena

申请号：EP15761376.1申请日：20150218公开号：EP31165B1公开日：20190410

摘要：The invention discloses a separation matrix for purification of biologicalparticles, comprising a plurality of particles having a porous core entity and a porousshell entity covering the core entity, wherein the core entity comprises at least 50micromole/ml primary amines present on covalently attached ligands displaying at leasttwo primary amines per ligand and the shell entity comprises less than 20 micromole/mlprimary amines The invention further discloses a method of purifying biological particlesand a method of manufacturing a separation matrix.

代理机构：Larsson, Jan Anders

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