Tetrahydrocyclopenta[c]acridine derivatives as kin

专利名称：Tetrahydrocyclopenta[c]acridine derivatives

as kinase inhibitors and biological

发明人：Philippe Olivier Belmont,Laurent

Meijer,Philip Cohen,Amaury Patin,JohannBosson,Peter Gregory Goekjian

申请号：US12735463申请日：20090119公开号：US08999955B2公开日：20150407

摘要：The invention relates to kinase inhibitors of the formula (I) in which —Rto R═H;ether or polyether, amino; NO; NH-carbamate; NH—CO—R, with R such as defined above;Nand derivatives thereof of the 1,2,3-triazole type; —R=—OH; halogen; —OR with R suchas defined above; OH-carbamate; OH-carbonate; NH, NH-carbamate; NH—CO—R, with Rsuch as defined above; Nand derivatives thereof of the 1,2,3-triazole type; N(R,R); —R′═Hor a C1-C12 alkyl, —R═H; R; (R or R′)—Si, with R such as defined above; optionally

substituted aryl, heteroaryl; halogen (iodine); alkynyl; —Rand R═H, C-Calkyl; —Rand R═H,R (or R′) such as defined above. These compounds can be used as kinase inhibitors inparticular for treating cancer.

申请人：Philippe Olivier Belmont,Laurent Meijer,Philip Cohen,Amaury Patin,JohannBosson,Peter Gregory Goekjian

地址：Lyons FR,Roscoff FR,Dundee GB,Villeurbanne FR,Etrembières FR,Lyons FR

国籍：FR,FR,GB,FR,FR,FR

代理机构：Nixon & Vanderhye P.C.

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