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Process for the preparation of 3-amino-pyrrolidine

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专利名称:Process for the preparation of 3-amino-pyrrolidine derivatives

发明人:Klinkhammer, Uwe,Spurr, Paul,Wang,

Shaoning

申请号:EP99100213.0申请日:19990108公开号:EP0928787B1公开日:20020605

摘要:The invention is concerned with a process for the manufacture of 3-amino-pyrrolidine derivatives of the formula    wherein by converting a compound of theformula    wherein in the presence of a primary amine of the formula RNH into thepyrrolidine derivative of the formula    wherein X and R have the aforementionedsignificances; which is subsequently reacted in the presence of RRNH under pressure; andwith the use of this process for the production of vinylpyrrolidinone-cephalosporinderivatives.

申请人:BASILEA PHARMACEUTICA AG

地址:CH

国籍:CH

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